Before that, I studied Information Engineering, Statistics, and Applied Cultural Sciences in Karlsruhe, Columbus and Heidelberg and obtained a BSc and Diplom (MSc) degree from the University of Karlsruhe and as a Fulbright-scholar a MSc degree from The Ohio State University.
Robust algorithms, statistical methods, and software tools for the analysis of biomedical data and bioinformatics
High dimensional genomics and proteomics data from next generation sequencing and mass spectrometry platforms
Integration of biomedical experiments and data sets
Statistical learning and computational statistics
Recent Journal Articles
M Kuhring, BY Renard (2012). iPiG: Integrating Peptide Spectrum Matches Into Genome Browser Visualizations. submitted
MS Lindner, BY Renard (2012). Metagenomic Abundance Estimation and Diagnostic Testing on Species Level. submitted
H Filbert, S Attig, N Bidmon, BY Renard, S Janetzki, U Sahin, MJP Welters, C Ottensmeier, SH van der Burg, C Gouttefangeas and CM Britten (2012). Serum-free freezing-media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols. submitted
M Loewer*, BY Renard*, J de Graaf, M Wagner, C Paret, C Kneip, O Tuereci, M Diken, C Britten, S Kreiter, M Koslowski, JC Castle, U Sahin (2012). Framework for confidence-based somatic mutation detection. submitted
BY Renard, B Xu, M Kirchner, F Zickmann, D Winter, S Korten, NW Brattig, A Tzur, H Steen, FA Hamprecht (2012). Overcoming Species Boundaries in Peptide Identification with BICEPS. Molecular & Cellular Proteomics, 2012, in press. [10.1074/mcp.M111.014167][Software]
H Soblik, AE Younis, M Mitreva, BY Renard, M Kirchner, F Geisinger, H Steen, NW Brattig (2011). Life cycle stage-resolved proteomic analysis of the excretome secretome from Strongyloides ratti - Identification of stage-specific protease. Molecular & Cellular Proteomics, 2011, 10(12):M111.010157. [10.1074/mcp.M111.010157]
BY Renard*, M Loewer*, Y Kuehne, U Reimer, A Rothermel, O Tuereci, JC Castle, U Sahin (2011). rapmad: Robust Analysis of Peptide Microarray Data. BMC Bioinformatics, 2011. 12:324 [10.1186/1471-2105-12-324][Software]
BM Voss, M Hanselmann, BY Renard, MS Lindner, U Koethe, M Kirchner, FA Hamprecht (2011). SIMA: Simultaneous Alignment of LC/MS Peak Lists. Bioinformatics, 2011: 27 (7): 987-993. [10.1093/bioinformatics/btr051][Software]
BY Renard, W Timm, M Kirchner, FA Hamprecht, H Steen. (2010). Estimating the Confidence of Peptide Identifications without Decoy Databases. Analytical Chemistry, 2010, 82(11):4314-4318. [10.1021/ac902892j][Software]
X Lou, BY Renard*, M Kirchner*, U Koethe, C Graf, C-T Lee, JAJ Steen, H Steen, MP Mayer, FA Hamprecht (2010). Deuteration Distribution Estimation with Improved Sequence Coverage for HDX/MS Experiments. Bioinformatics, 2010, 26(12):1535-1541.[10.1093/bioinformatics/btq165][Software]
BY Renard*, M Kirchner*, U Koethe, DJ Pappin, FA Hamprecht, H Steen, JJ Steen (2010). Computational Protein Profile Similarity Screening for Quantitative Mass Spectrometry Experiments. Bioinformatics, 2010, 26(1):77-83. [10.1093/bioinformatics/btp607][Software]
N Ozlu, F Monigatti, BY Renard, CM Field, H Steen, TJ Mitchison, JJ Steen (2010). Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Molecular & Cellular Proteomics, 2010, 9(2):336-350. [10.1074/mcp.M900308-MCP200]
BY Renard, M Kirchner, F Monigatti, AR Ivanov, J Rappsilber, D Winter, JAJ Steen, FA Hamprecht, H Steen (2009). When Less Can Yield More - Computational Preprocessing of MS/MS Spectra for Peptide Identification. PROTEOMICS, 2009, 9(21):4978-4984. [10.1002/pmic.200900326][Software]
M Hanselmann, U Koethe, M Kirchner, BY Renard, ER Amstalden, K Glunde, RMA Heeren, FA Hamprecht (2009). Toward Digital Staining using Imaging Mass Spectrometry and Random Forests. Journal of Proteome Research, 8(7), 3558-3567. [10.1021/pr900253y]
BY Renard*, M Kirchner*, H Steen, JAJ Steen, FA Hamprecht (2008). NITPICK: Peak Identification for Mass Spectrometry Data. BMC Bioinformatics 2008, 9:355 [10.1186/1471-2105-9-355][Software]
M Hanselmann, M Kirchner*, BY Renard*, ER Amstalden, K Glunde, RMA Heeren, FA Hamprecht (2008). Concise Representation of Mass Spectrometry Images by Probabilistic Latent Semantic Analysis. Analytical Chemistry, 80(24):9649-9658. [10.1021/ac801303x][Software]
Recent Conference Contributions
BY Renard, B Xu, M Kirchner, F Zickmann, D Winter, S Korten, NW Brattig, A Tzur, FA Hamprecht, H Steen (2012). Overcoming species boundaries in protein identification with a Bayesian Information Criterion-driven Error-tolerant Peptide Search (BICEPS). Conference of the American Society for Mass Spectrometry (ASMS) 2012.
M Kirchner, M Wilhelm, D Sichau, B Xu, BX Kausler, T Kroeger, A Kreshuk, X Lou, BY Renard, FA Hamprecht, JA Steen, H Steen (2012). Introducing the Mass Spectrometry Toolkit (MSTK): Efficient Software Development for MS Data Analysis. Conference of the American Society for Mass Spectrometry (ASMS) 2012.
MS Lindner, BY Renard (2011).
Risks for Specificity and Sensitivity in Metagenomic Classification Experiments
German Conference on Bioinformatics (GCB) 2011.
F Zickmann, BY Renard (2011).
Influence of Target and Decoy Database Size on Peptide Identification Confidence,
German Conference on Bioinformatics (GCB) 2011.
M Löwer*, BY Renard*, J de Graaf, M Diken, Ö Türeci, C Britten, S Kreiter, M Koslowski, JC Castle, U Sahin (2011).
Target Identification for Immunotherapies: a framework for confidence-based somatic mutation detection and application to B16 melanoma cells,
Cancer Immunotherapy Annual Meeting (CIMT) 2011.
H Filbert, S Attig, N Bidmon, BY Renard, S Janetzki, U Sahin, MJP Welters, C Ottensmeier, SH van der Burg, C Gouttefangeas, CM Britten (2011).
Serum-free freezing-media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols,
Cancer Immunotherapy Annual Meeting (CIMT) 2011.
M Hanselmann, J Röder, U Köthe, BY Renard, A Kreshuk, RMA Heeren, FA Hamprecht (2010).
Active Learning for Efficient Labeling and Classification of Imaging Mass Spectrometry data, Conference of the American Society for Mass Spectrometry (ASMS) 2010.
A Kreshuk, M Kirchner, BY Renard, D Winter, BX Kausler, X Lou, M Hanselmann, JAJ Steen, H Steen, WD Lehmann, FA Hamprecht (2010).
Automatic Relative Quantification for High-Resolution LC/MS 16/18O Labeling Experiments, Conference of the American Society for Mass Spectrometry (ASMS) 2010.
BX Kausler, M Kirchner, A Kreshuk, BY Renard, H Hahne, B Küster, JAJ Steen, H Steen, FA Hamprecht (2010).
Resolution as a function of m/z for TOF, FT-ICR, and Orbitrap: predicted and confirmed. Conference of the American Society for Mass Spectrometry (ASMS) 2010.
M Hanselmann,U Koethe, BY Renard, M Kirchner,RMA Heeren,FA Hamprecht (2009).
Multivariate Watershed Segmentation of Compositional Data.
Proc. of the 15th Int. Conf. on Discrete Geometry for Computer Imagery (DGCI) Lecture Notes in Computer Science, Springer(2009), 5810:180-192.
BY Renard, F Monigatti,M Kirchner,AR Ivanov,J Rappsilber,JAJ Steen,FA Hamprecht,H Steen. (2009).
Computational MS/MS Spectra Preprocessing - a Free Lunch.Conference of the American Society for Mass Spectrometry (ASMS) 2009.
M Kirchner*,BY Renard*,U Koethe,JAJ Steen,H Stee,FA Hamprecht. (2009).
Automatic Computational Protein Co-Regulation Screening for Quantitative Mass Spectrometry Experiments. Conference of the American Society for Mass
Spectrometry (ASMS) 2009.
A Kreshuk, M Kirchner, BY Renard,D Winter,H Steen,JAJ Steen, WD Lehmann,FA Hamprecht. (2009).
Automatic Quantification of 16/18O-Labeled LC/MS Data. Conference of the American Society for Mass Spectrometry (ASMS) 2009.
BM Voss, BY Renard,A Kreshuk,M Hanselmann,U Koethe,H Steen,JAJ Steen, M Kirchner,FA Hamprecht. (2009).
Simultaneous Multiple Alignment for LC/MS Peak Lists. Conference of the American Society for Mass Spectrometry (ASMS) 2009.
N Ozlu, F Monigatti, BY Renard, C Field, H Steen, T Mitchison, JAJ Steen. (2009)
Large-Scale Proteomic Analyses reveal that Aurora B is a Master Kinase Regulating the C-phase Cytoskeleton,
Conference of the American Society for Mass Spectrometry (ASMS) 2009.
X Lou, BY Renard*, M Kirchner*, U Koethe,C Graf,JAJ Steen,H Steen, MP Mayer,FA Hamprecht. (2009).
HeXicon++: Automating HDX Data Analysis.Conference of the American Society for Mass Spectrometry (ASMS) 2009.
M Hanselmann,U Koethe,M Kirchner*, BY Renard*,ER Amstalden,K Glunde, RMA Heeren,FA Hamprecht. (2009).
Automated Classification and Grading of Tumors in Mass Spectrometric Images using postprocessed Random Forests.
Conference of the American Society for Mass Spectrometry (ASMS) 2009.
BY Renard*, M Kirchner*, F Monigatti, JAJ Steen, H Steen and FA Hamprecht (2008).
Optimal Significane Determination in iTRAQ experiments,
Conference of the American Society for Mass Spectrometry (ASMS) 2008.
BY Renard*, M Kirchner*, JAJ Steen, H Steen and FA Hamprecht (2008).
STRAP2: Reliable, Hierarchical Feature Extraction from Multicomponent Mass Spectra,
Conference of the American Society for Mass Spectrometry (ASMS) 2008.
K Hanselmann, BY Renard*, M Kirchner*, A Kharchenko, L Klerk, U Koethe, RMA Heeren and FA Hamprecht (2008).
Concise representation of MS Images by Probabilistic Latent Semantic Analysis,
Conference of the American Society for Mass Spectrometry (ASMS) 2008.
S Boppel, BY Renard*, M Kirchner*, H Steen, U Koethe and FA Hamprecht (2008).
Sparse Profile Reconstruction for LC/MS Feature Extraction,
Conference of the American Society for Mass Spectrometry (ASMS) 2008.
X Lou, M Kirchner*, BY Renard*, U Koethe, H Steen, MA Mayer and FA Hamprecht (2008).
Fully Automated HX-MS Data Analysis with Complete Deuteration Distribution Estimation,
Conference of the American Society for Mass Spectrometry (ASMS) 2008.
